Fig. 3

Inversion visualization in IGV. a Inversion region produces a large number of read pairs with the same orientation. The green read pair means both of the ends are mapped on the forward strand. The blue part means both of the ends are mapped on the reverse strand. b One end unmapped with the red line surrounded happens near the inversion, which means that an end mapping to the reference genome fails in the read pair near the inversion breakpoint. c When a read is mapped on a breakpoint of inversion, soft-clipped read occurs, in which the continuous bases are unmapped reflection as the color block. d ISPE is the distance between two ends in a read pair, ISPE is abnormally called discordant read pair perhaps indicates inversion occurs. e The overall effect of inversion on a genomic region