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Fig. 3 | BMC Genomics

Fig. 3

From: Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites

Fig. 3

Sense/antisense and coding/noncoding apportionments of PQSs in Laveranian genomes. Bar plots show coding/non-coding and sense/antisense apportionments of PQSs in Laveranian genomes. PQSs were considered ‘antisense’ if they were on the opposite strand relative to their nearest gene. Telomeric-PQSs were excluded. Panels a and b show the number of coding-PQSs as a percentage of total PQSs (red), and the number of coding, var-associated PQSs as a percentage of total var-associated PQSs (black), found by QGRS Mapper (A) and G4 Hunter (B). Panel c shows the number of coding, antisense, var-associated PQSs as a percentage of total coding, var-associated PQSs, found by QGRS Mapper (blue) and G4 Hunter (orange). For each algorithm, the difference between the percentage of coding, var-associated PQSs that were sense versus antisense was assessed (QGRS Mapper: t-stat = 11.80, p-value = 5.81 × 10− 8; G4 Hunter: t-stat = 4.43, p-value = 8.19 × 10− 4)

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BMC Genomics

ISSN: 1471-2164

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