Table 1 Differential expression (DE) of miRNAs across tissues, with developmental stage, and in tissue-specific developmental comparisons
Comparison | downregulated miRNAs | upregulated miRNAs | Total DE |
|---|---|---|---|
Tissue analysis: relative to all other sample types | |||
 Brain | 76 | 169 | 245 |
 Heart | 5 | 33 | 38 |
 Muscle | 6 | 50 | 56 |
 Plasma | 84 | 67 | 151 |
Age analysis: adult relative to pup in all sample types combined | |||
 Adult vs. Pup | 46 | 34 | 80 |
Age x Tissue: adult relative to pup for each tissue | |||
 Brain | 43 | 55 | 98 |
 Heart | 9 | 20 | 29 |
 Muscle | 67 | 26 | 93 |
 Plasma | 0 | 0 | 0 |