Table 1 SNPs demonstrating significant association to CHD in the across-breed CMH test for stratified data
From: An across-breed validation study of 46 genetic markers in canine hip dysplasia
SNP | Location in CanFam3.1 | Allele (minor / major) | Raw P-value (PRAW) | Permuted P-value (PGEN) | OR (95% CI) | Origins of the SNP (study, breeds, and phenotypes) |
|---|---|---|---|---|---|---|
ss7212922120 | CFA1: 45382633 | A/C | 7.4 × 10–03 | 8.4 × 10–03 | 1.30 [1.07–1.57] | Mikkola et al. (2019) [13]/ German Shepherd / FCI hip score |
ss7212922135 | CFA14: 56572744 | T/C | 0.027 | 0.028 | 1.19 [1.02–1.38] | Pfahler & Distl (2012) [6]/ Bernese Mountain dog / FCI hip score |
ss7212922151 | CFA26: 14157064 | T/C | 8.8 × 10–03 | 0.011 | 1.26 [1.06–1.49] | Fels & Distl (2014) [7]/ German Shepherd/ FCI hip score |
ss7212922139 | CFA37: 14299531 | C/A | 0.030 | 0.032 | 0.84 [0.72–0.98] | Zhou et al. (2010) [4]/ Multiple breeds and breed crosses/ OA |