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Fig. 5 | BMC Genomics

Fig. 5

From: The immune-modulating pregnancy-specific glycoproteins evolve rapidly and their presence correlates with hemochorial placentation in primates

Fig. 5

The most highly expressed human and OWM PSG genes lack the disintegrin-like RGD motif. The relative expression frequencies of PSG were estimated by counting the clones matching N exon nucleotide sequences of the different PSG genes present in human, baboon and rhesus monkey placental EST libraries. Only hits with E val = 0.0 were assigned to a given gene. A total number of 2302, 404 and 345 PSG clones, were identified in human, baboon and rhesus monkey, respectively. The presence of the LYHY motif needed for latent TGFβ1 secretion and the disintegrin-like RGD motif are shown as red and blue filled-in circles, respectively. The presence of RGD motifs with conservative amino acid changes (KGD, RGE) are indicated by blue open circles. Of note: The PSG genes were numbered arbitrarily. Therefore, no orthology can be inferred for genes with the same numbers between different species

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