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Fig. 3 | BMC Genomics

Fig. 3

From: Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

Fig. 3

(a) Ingenuity pathway analysis (IPA) analysis of functional associations between the top scoring adrenal genes upregulated in the KK/HlJ strain according to magnitude of fold changes between the contrast groups: Set 1 (KK-M vs. C57-M) and Set 3 (KK-F vs. C57-F) ≥± 1.4-fold (P≤0.05). The shapes represent the molecular classes of the proteins and the intensity of the green-colored nodes represent the extent of upregulated expression, with dark green representing higher fold changes. Direct and indirect interactions are indicated by solid and dashed lines, respectively. (b) Top pancreatic network of genes upregulated in the C57BL/6 J strain, in which the intensity of the red-colored nodes represent the extent of upregulated expression

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BMC Genomics

ISSN: 1471-2164

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