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Table 5 Comparing p-values for EcoCyc VALSYN-PWY and KEGG map00290

From: Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics

Count of Significantly Expressed Genes EcoCyc p-value Corrected for Multiple Comparisons Native KEGG p-value Corrected for Multiple Comparisons
9 1.6×10−22 5.8×10−20 3.9×10−20 4.6×10−18
8 1.8×10−19 6.3×10−17 8.1×10−18 9.6×10−16
7 9.7×10−17 3.4×10−14 1.5×10−15 1.8×10−13
6 3.5×10−14 1.3×10−11 2.5×10−13 3.0×10−11
5 9.6×10−12 3.4×10−9 3.9×10−11 4.6×10−9
4 2.1×10−9 7.5×10−7 5.4×10−9 6.5×10−7
3 3.8×10−7 1.4×10−4 7.0×10−7 8.4×10−5
2 6.0×10−5 2.1×10−2 8.4×10−5 1.0×10−2
1 8.2×10−3 1.0 9.4×10−3 1.0
  1. Corrected p-values use Bonferroni as a ’worst case’ correction as discussed in the text
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