Table 3 KEGG pathway enrichment analysis of wild-type and transgenic tilapia fish expressing delta-6 desaturase plus delta-5 desaturase (D56) infected with V. vulnificus for 6 h

onl00983

Drug metabolism - other enzymes

10

7E-06

onl00330

Arginine and proline metabolism

8

1E-05

onl00620

Pyruvate metabolism

6

0.0001

onl00561

Glycerolipid metabolism

7

0.0003

onl00380

Tryptophan metabolism

6

0.0003

onl00100

Steroid biosynthesis

4

0.0004

onl00500

Starch and sucrose metabolism

5

0.0006

onl00982

Drug metabolism - cytochrome P450

6

0.001

onl00340

Histidine metabolism

4

0.0011

onl00480

Glutathione metabolism

7

0.0013

onl00071

Fatty acid degradation

5

0.0015

onl00010

Glycolysis / Gluconeogenesis

6

0.0029

onl00410

beta-Alanine metabolism

4

0.003

onl00053

Ascorbate and aldarate metabolism

4

0.004

onl01230

Biosynthesis of amino acids

6

0.0044

onl04145

Phagosome

11

0.006

onl00980

Metabolism of xenobiotics by cytochrome P450

5

0.0061

onl00430

Taurine and hypotaurine metabolism

3

0.0082

onl00220

Arginine biosynthesis

3

0.0091

onl00260

Glycine, serine and threonine metabolism

4

0.0091

onl04060

Cytokine-cytokine receptor interaction

11

0.011

onl03060

Protein export

3

0.0121

onl01200

Carbon metabolism

7

0.0131

onl00280

Valine, leucine and isoleucine degradation

4

0.0165

onl04672

Intestinal immune network for IgA production

6

0.0199

onl04350

TGF-beta signaling pathway

6

0.027

onl00520

Amino sugar and nucleotide sugar metabolism

4

0.028

onl00270

Cysteine and methionine metabolism

4

0.0318

onl00310

Lysine degradation

4

0.0449

onl00360

Phenylalanine metabolism

2

0.0454