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Table 6 The association of 30 SNPs with BDNF expression in each of the five regions

From: Genotype-expression interactions for BDNF across human brain regions

 

ALT

Freq

Cerebellum

Cortex

Nucleus accumbens

Caudate

Cerebellar Hemisphere

dbSNP_ID

REF

ALT

Corr_r

P value

Corr_r

P value

Corr_r

P value

Corr_r

P value

Corr_r

P value

rs2049045

G

C

0.1531

0.5676

4.73E-16

0.5758

1.93E-14

0.4088

3.02E-07

0.4473

2.14E-08

0.5266

7.51E-11

rs6265

C

T

0.1555

0.584

4.12E-17

0.5974

1.10E-15

0.4084

3.09E-07

0.4666

4.27E-09

0.5475

9.10E-12

rs1829469

A

G

0.1675

0.5391

3.97E-14

0.4754

1.17E-09

0.3581

9.10E-06

0.3918

1.43E-06

0.5226

1.30E-10

rs16917237

G

T

0.1699

0.5185

3.21E-13

0.4789

7.42E-10

0.3506

1.44E-05

0.4025

6.23E-07

0.5127

2.81E-10

rs35038967

T

A

0.1699

0.5185

3.21E-13

0.4789

7.42E-10

0.3506

1.44E-05

0.4025

6.23E-07

0.5127

2.81E-10

rs12575096

A

G

0.1699

0.5185

3.21E-13

0.4789

7.42E-10

0.3506

1.44E-05

0.4025

6.23E-07

0.5127

2.81E-10

rs11030104

A

G

0.1722

0.5452

1.05E-14

0.4978

1.21E-10

0.3672

5.12E-06

0.3867

1.84E-06

0.5254

8.45E-11

rs71311904

C

CCATTT

0.1722

0.4743

4.96E-11

0.455

6.28E-09

0.3561

1.03E-05

0.4131

2.93E-07

0.4562

3.43E-08

rs34379767

G

A

0.1731

0.5075

1.20E-12

0.476

1.11E-09

0.3694

4.47E-06

0.4268

1.18E-07

0.4994

9.39E-10

rs4923466

C

A

0.1731

0.5086

1.22E-12

0.4866

4.13E-10

0.3694

4.47E-06

0.4334

6.39E-08

0.4994

9.39E-10

rs12419948

T

A

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs925947

G

T

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs16917204

G

C

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs10501087

T

C

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs36070170

A

AT

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs4923463

A

G

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs11030099

C

A

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs11030100

G

T

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3773

3.39E-06

0.5367

2.74E-11

rs4923464

C

T

0.1746

0.5518

4.31E-15

0.5069

4.90E-11

0.3672

5.12E-06

0.3764

3.60E-06

0.5367

2.74E-11

rs113145808

T

C

0.1746

0.5075

1.20E-12

0.4758

9.88E-10

0.3694

4.47E-06

0.4334

6.39E-08

0.4994

9.39E-10

rs12801337

G

A

0.1746

0.5075

1.20E-12

0.4758

9.88E-10

0.3694

4.47E-06

0.4334

6.39E-08

0.4994

9.39E-10

rs12790234

A

G

0.1746

0.5075

1.20E-12

0.4758

9.88E-10

0.3694

4.47E-06

0.4334

6.39E-08

0.4994

9.39E-10

rs4922793

A

G

0.1755

0.5019

2.69E-12

0.4918

2.53E-10

0.3694

4.47E-06

0.4451

2.86E-08

0.4782

5.83E-09

rs988748

C

G

0.8182

−0.4983

3.49E-12

−0.4896

2.71E-10

−0.3755

3.02E-06

−0.4334

6.39E-08

−0.476

7.02E-09

rs10767664

T

A

0.8182

−0.4983

3.49E-12

−0.4896

2.71E-10

−0.3755

3.02E-06

−0.4334

6.39E-08

−0.476

7.02E-09

rs2030323

A

C

0.8182

−0.4983

3.49E-12

−0.4896

2.71E-10

−0.3755

3.02E-06

−0.4334

6.39E-08

−0.476

7.02E-09

rs6484320

T

A

0.8206

− 0.514

5.51E-13

− 0.4896

2.71E-10

− 0.3755

3.02E-06

− 0.4334

6.39E-08

− 0.497

1.16E-09

rs444654

T

G

0.8206

−0.514

5.51E-13

−0.4896

2.71E-10

−0.3755

3.02E-06

−0.4334

6.39E-08

−0.497

1.16E-09

rs7926362

A

C

0.8221

−0.5099

1.06E-12

−0.4896

2.71E-10

−0.3768

3.00E-06

−0.4352

6.21E-08

−0.497

1.16E-09

rs7103411

C

T

0.8230

−0.5098

9.16E-13

−0.4896

2.71E-10

−0.3847

1.63E-06

−0.4334

6.39E-08

−0.48

5.03E-09

  1. Note: REF Reference allele; ALT Alternative allele; Freq Frequency; Corr_r Spearman correlation estimates, Correlations and p-values across some SNPs are identical due to presence within a haplotype block
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