Fig. 3

Temporal-spatial patterns of aging-related differentially expressed genes (DEGs). a Venn diagram of aging-related DEGs of different organs. The total number of organ-specific DEGs is shown in parentheses. b Bar chart illustrating the DEGs of different organs. The matrix of solid and empty circles at the left illustrates the “presence” (solid red) or “absence” (empty) of the organ in each intersection. The bar at the right represents the number of DEGs in each intersection. The representative enriched GO and Kyoto Encyclopedia of Genes and Genomes (KEGG) terms for the gene sets are shown on the right. c Bar chart illustrating the number of DEGs at 14–21 and 21–28 D within each organ. The DEGs are classified as “up” (marked in red) for the genes with an increased expression during this period and “down” (marked in blue) for the genes with a decreased expression in this period. The numbers at the top of the bar correspond to the numbers of DEGs