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Table 2 The 30 most down-regulated DEGs in the magnum of laying compared to non-laying hens

From: RNA sequencing-based analysis of the magnum tissues revealed the novel genes and biological pathways involved in the egg-white formation in the laying hen

Gene Name

Gene Description

Fold Change

RACGAP1

Rac GTPase activating protein 1

16.6262

ECT2

Epithelial cell transforming 2

14.9228

PLK1

Polo like kinase 1

14.0534

BUB1

BUB1 mitotic checkpoint serine/threonine kinase

13.9712

SMC2

Structural maintenance of chromosomes 2

13.8266

BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

13.7985

NUF2

NUF2, NDC80 kinetochore complex component

13.3569

RRM2

Ribonucleotide reductase regulatory subunit M2

12.9268

CDCA7

Cell division cycle associated 7

12.8785

CENPF

Centromere protein F

12.7394

NEK2

NIMA related kinase 2

12.5734

ASPM

Abnormal spindle microtubule assembly

12.2945

BRCA1

BRCA1(Breast cancer)

12.2056

TOP2A

Topoisomerase (DNA) II alpha

11.5891

NUSAP1

Nucleolar and spindle associated protein 1

11.1474

BORA

Bora, aurora kinase A activator

11.0740

KIF15

Kinesin family member 15

10.6809

CCNB3

CCNB3 (cyclin B3)

10.6117

ARHGAP19

ARHGAP19

10.4602

STMN1

Stathmin 1

10.4540

E2F7

E2F transcription factor 7

10.4150

KNTC1

Kinetochore associated 1

10.0559

PTX3

Pentraxin 3

9.9658

CENPI

Centromere protein I

9.8662

GTSE1

G2 and S-phase expressed 1

9.7306

KIF2C

Kinesin family member 2C

9.6465

Gga.19339

Family with sequence similarity 72, member A

9.5760

MELK

Maternal embryonic leucine zipper kinase

9.4771

KIF4A

Kinesin family member 4A

9.2900

CENPE

Centromere protein E

9.2869

  1. Transcripts from the magnum of layers and non-layers were aligned to the chicken genome and mapped genes with at least a 3-fold change difference and Benjamini Hochberg q-value < 0.05 were considered differentially expressed. DEGs, differentially expressed genes