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Fig. 7 | BMC Genomics

Fig. 7

From: A systematic bioinformatics approach for large-scale identification and characterization of host-pathogen shared sequences

Fig. 7

Dengue virus type (DV) 2 (strain Jamaica/1409/1983)-human protein-protein interaction (PPI) network. The DV proteins associated with major hub, human proteins (PTBP1, ACTC1 and ACTA2, among others; Table 7). Cyan nodes denote viral proteins with red edges linking to other nodes; blue nodes denote human proteins with grey edges linking to various nodes; and the yellow node denotes the hub protein with the highest degree of nodes. The PTBP1 is a hub connecting major nodes, including NS2A-alpha, which connects other viral and human nodes to PTBP1 and to other nodes of the DV-human PPI network

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