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Fig. 3 | BMC Genomics

Fig. 3

From: LncRNA:DNA triplex-forming sites are positioned at specific areas of genome organization and are predictors for Topologically Associated Domains

Fig. 3

Relationships of Triplex forming sites with domain size, CTCF sites, and genomic annotation. (A) A small negative correlation between the size of domains (x-axis) and the normalized overlap between TFSs and TADs (y-axis). The Pearson correlation coefficients are indicated for each cell line. (B) Distances between closest pairs of CTCF sites and TFSs are not significantly different from random and TFSs (Chi-Square test, p-value > 0.1 for each cell line). The plots are histogram plots of the distances with four bins. (C) Genomic annotation (x-axis) of lncRNA:DNA TFSs reveal major fraction (y-axis) of them are in promoter, intronic, intergenic, and 3’UTR regions.

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