Table 1 GWAS showing genes significantly correlating to bacteraemia using the presence (+) and absence (-) of each gene in 423 isolates (Bonferroni p value < 0.001 and a odds ratio > 1), * genes specific to Clade 1
Gene | Function | Bacteraemia Isolates N (%) | Non Bacteraemia Isolates N (%) |
|---|---|---|---|
clfA | Clumping factor A | 240 (79.4) | 53 (43.8) |
hsdM_1 | Type I restriction enzyme EcoKI M protein | 269 (89) | 55 (45) |
ohrR | Organic hydroperoxide resistance transcriptional regulator* | 103 (34.1) | 0 |
acul | Putative acrylyl-CoA reductase Acul* | 102 (33.7) | 0 |
ypuA | Hypothetical protein* | 105 (34.7) | 1 (0.7) |
hutl_2 | Hypothetical protein* | 101 (33.4) | 1 (0.7) |
entE | Enterotoxin type E* | 101 (33.4) | 0 |
soj | Chromosome partitioning ATPase* | 101 (33.4) | 1 (0.7) |
entA_2 | Enterotoxin type A* | 99 (32.7) | 0 |