Fig. 5
From: UniBind: maps of high-confidence direct TF-DNA interactions across nine species
Correlation between enhancer activity and TF binding. For each enhancer predicted using Cap Analysis of Gene Expression (CAGE) by the FANTOM5 consortium, we computed the number of TFs with overlapping TFBSs in the robust collection of UniBind (x-axis). The figure provides, for each value of the number of TFs found to bind in enhancers, the median (blue line) together with the 10th to 90th percentiles (grey area) of cell type specific activity of these enhancers. The expression measures were derived from CAGE (capturing enhancer RNA expression). The specificity of activity (y-axis) is provided within the [0; 1] range with 0 representing ubiquitous enhancer activity and 1 exclusive expression activity