Fig. 1From: Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in miceEffects of maternal cold exposure on placental and fetal weight. (A) Scheme for maternal exposure to two different environmental temperatures. Female C57BL/6 J mice were acclimated at 28 °C (n = 7) or 18 °C (n = 7) for 1 week and mated with males. Pregnant females were maintained at respective temperature until embryonic day 18.5. Animal images are taken from freely available online pictures in the public domain. (B) Gene expression analysis of BAT samples from dams exposed at 28 °C (n = 7) or 18 °C (n = 7). (C) Body weight of pregnant dams during pregnancy (n = 7 per group). (D) Weight of placentas (7 litters per group). (E) Litter size per pregnancy. (F) Weight of fetuses (7 litters per group). All data are presented as the mean ± SEM. **P < 0.01, ***P < 0.001, #P < 0.0001 determined by Student’s t testBack to article page