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Table 5 Logistic regression analysis of the association between cg04481923 methylation level in VTRNA2-1 gene and preterm births (n = 82)

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Methylation β-value SE Odds ratio 95 % CI p-value
Age -0.057 0.035 0.945 0.882–1.012 0.104
Season -0.582 0.238 0.559 0.350–0.892 0.015
Parity 0.389 0.313 1.475 0.798–2.727 0.215
VTRNA2-1a 1.185 0.574 3.269 1.061–10.069 0.039
WBC count 0.211 0.075 1.235 1.066–1.431 0.005
  1. β-values and SE estimated using the multivariable logistic regression model
  2. VTRNA2-1 vault RNA 2 − 1
  3. aIt was divided into two groups based on the methylation level of VTRNA2-1 promoter: a hypomethylated group (< 13 %, n = 28) and an elevated methylated group (30–60 %, n = 54)