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Table 2 GO enrichment analysis of the DEGs of E. granulosus

From: Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine

Categorya GO term ID GO term description p value DEG involved
Cellular component GO:0044464 Cell part 2.25 × 10− 7 320
GO:0044424 Intracellular part 2.95 × 10− 6 272
GO:0005891 Voltage-gated calcium channel complex 2.53 × 10− 5 7
GO:0034704 Calcium channel complex 6.26 × 10− 5 7
GO:0043229 Intracellular organelle 0.000177 148
GO:0043226 Organelle 0.000224 148
GO:0032991 Macromolecular complex 0.000849 176
GO:0016021 Integral component of membrane 0.000866 135
GO:0031224 Intrinsic component of membrane 0.000876 135
GO:0044425 Membrane part 0.0013 157
Molecular function GO:0005488 Binding 8.54 × 10− 6 427
GO:0005245 Voltage-gated calcium channel activity 2.53 × 10− 5 7
GO:0097159 Organic cyclic compound binding 0.000336 286
GO:1,901,363 Heterocyclic compound binding 0.000336 286
GO:0004930 G-protein coupled receptor activity 0.000512 19
GO:0003676 Nucleic acid binding 0.000647 169
GO:0043565 Sequence-specific DNA binding 0.000827 36
GO:0043167 Ion binding 0.000974 278
GO:0043169 Cation binding 0.00201 158
GO:0004872 Receptor activity 0.00227 35
Biological process GO:0006950 Response to stress 9.19 × 10− 6 39
GO:0050896 Response to stimulus 2.64 × 10− 5 40
GO:0006355 Regulation of transcription, DNA-templated 0.000521 85
GO:0034765 Regulation of ion transmembrane transport 0.00192 9
GO:0034762 Regulation of transmembrane transport 0.00192 9
GO:0051049 Regulation of transport 0.00335 10
GO:0034728 Nucleosome organization 0.00396 11
GO:0006334 Nucleosome assembly 0.00396 11
GO:0065004 Protein-DNA complex assembly 0.00396 11
GO:0071824 Protein-DNA complex subunit organization 0.00396 11
  1. aTop 10 terms for each category