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Table 2 GO enrichment analysis of the DEGs of E. granulosus

From: Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine

Categorya

GO term ID

GO term description

p value

DEG involved

Cellular component

GO:0044464

Cell part

2.25 × 10− 7

320

GO:0044424

Intracellular part

2.95 × 10− 6

272

GO:0005891

Voltage-gated calcium channel complex

2.53 × 10− 5

7

GO:0034704

Calcium channel complex

6.26 × 10− 5

7

GO:0043229

Intracellular organelle

0.000177

148

GO:0043226

Organelle

0.000224

148

GO:0032991

Macromolecular complex

0.000849

176

GO:0016021

Integral component of membrane

0.000866

135

GO:0031224

Intrinsic component of membrane

0.000876

135

GO:0044425

Membrane part

0.0013

157

Molecular function

GO:0005488

Binding

8.54 × 10− 6

427

GO:0005245

Voltage-gated calcium channel activity

2.53 × 10− 5

7

GO:0097159

Organic cyclic compound binding

0.000336

286

GO:1,901,363

Heterocyclic compound binding

0.000336

286

GO:0004930

G-protein coupled receptor activity

0.000512

19

GO:0003676

Nucleic acid binding

0.000647

169

GO:0043565

Sequence-specific DNA binding

0.000827

36

GO:0043167

Ion binding

0.000974

278

GO:0043169

Cation binding

0.00201

158

GO:0004872

Receptor activity

0.00227

35

Biological process

GO:0006950

Response to stress

9.19 × 10− 6

39

GO:0050896

Response to stimulus

2.64 × 10− 5

40

GO:0006355

Regulation of transcription, DNA-templated

0.000521

85

GO:0034765

Regulation of ion transmembrane transport

0.00192

9

GO:0034762

Regulation of transmembrane transport

0.00192

9

GO:0051049

Regulation of transport

0.00335

10

GO:0034728

Nucleosome organization

0.00396

11

GO:0006334

Nucleosome assembly

0.00396

11

GO:0065004

Protein-DNA complex assembly

0.00396

11

GO:0071824

Protein-DNA complex subunit organization

0.00396

11

  1. aTop 10 terms for each category