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Table 2 Genomic location of the significant Quantitative Trait Loci (QTL) at 90 and 95% genome wide significant thresholds associated with polyp counts in SB1, SB2, SB3, Colon and total polyps in the entire intestines (SB1–3 and colon) regions of different CC lines. QTL associated with polyp counts detected on different chromosomal regions. Experiment-wide thresholds of significance at *P% of 50, 90 and 95% levels are presented for each trait, accordingly

From: Genetic mapping of novel modifiers for ApcMin induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice

Trait logP Chrs QTL Peak (Mb) CI 50%
Size
(Mb)
[Genes]
CI 90%
Size
(Mb)
[Genes]
CI 95%
Size
(Mb)
[Genes]
*90% **95%
SB1 3.71 4.43 Chr3 Mom19** 13.839 13.434–14.321 (0.88) [12] 11.203–17.131 (5.93) [49] 9.902–19.627 (9.72) [104]
Chr12 Mom20* 111.371 110.004–113.284 (3.28) [104] 103.706–117.303 (13.60) [610] 102.018–118.857 (16.84) [670]
SB2 3.83 4.11 Chr10 Mom21** 18.805 17.208–20.747 (3.54) [46] 9.550–27.338 (17.79) [234] 8.902–28.471 (19.57) [245]
Chr16 Mom22** 53.511 52.785–56.096 (3.31) [34] 48.038–62.078 (14.04) [186] 45.522–63.132 (17.61) [226]
Mom23** 73.216 72.224–73.812 (1.59) [9] 69.722–76.406 (6.68) [51] 68.716–78.148 (9.43) [73]
SB3 3.90 4.20 Chr6 Mom24** 146.203 145.502–146.376 (0.87) [8] 140.899–147.303 (6.40) [103] 138.051–147.806 (9.76) [135]
Chr12 Mom25** 113.449 112.966–113.893 (0.93) [96] 110.997–115.709 (4.71) [299] 109.825–116.663 (6.84) [375]
Chr9 Mom26* 37.552 35.326–39.645 (4.32) [176] 32.692–42.502 (9.81) [271] 32.557–42.557 (10.00) [273]
Chr10 Mom21* 18.805 16.268–20.395 (4.13) [48] 9.921–25.465 (15.54) [211] 8.950–27.582 (18.63) [238]
Colon 3.87 4.19 Chr6 Mom27** 35.915 35.651–36.331 (0.68) [3] 35.031–37.665 (2.63) [27] 34.720–38.392 (3.67) [59]
Total polyps 3.86 4.23 Chr12 Mom20** 111.636 111.349–112.016 (0.67) [26] 109.935–113.616 (3.68) [156] 109.525–113.920 (4.39) [284]
Chr16 Mom22** 53.489 51.882–56.475 (4.59) [42] 45.709–62.530 (16.82) [211] 44.055–63.294 (19.24) [258]
Mom23** 73.556 72.068–74.972 (2.90) [18] 68.468–80.424 (11.96) [93] 65.848–83.013 (17.16) [119]
  1. **95%, *90% levels of genome wide significance thresholds