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Table 5 Candidate gene list identified within the mapped QTL, Mom19–27, based on merge analysis and using MGI data base

From: Genetic mapping of novel modifiers for ApcMin induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice

Trait Chromosome Mom Gene  
SB2 16 Mom 22 / Mom 23 Eih3 ethanol induced hypothermia 3
Mom 22 / Mom 23 Bwtn1 body weight at necropsy 1
Mom 22 / Mom 23 Aod1a autoimmune ovarian dysgenesis 1a
Mom 22 / Mom 23 Skts-fp3 skin tumor susceptibility in FVB and PWK 3
Mom 22 / Mom 23 Eae41 experimental allergic encephalomyelitis susceptibility 41
Mom 22 / Mom 23 Diobq diet-induced obesity QTL
Mom 22 / Mom 23 Dice1b determination of interleukin 4 commitment 1b
Mom 23 Eae11 experimental allergic encephalomyelitis susceptibility 11
Mom 23 Lith14 lithogenic gene 14
Mom 23 Pod plasticity of ocular dominance
  Sluc27 susceptibility to lung cancer 27
  Etia ethanol induced activation
  Bpq9 blood pressure QTL 9
  Tgq28 triglyceride QTL 28
  Pgia10 proteoglycan induced arthritis 10
SB3 9 Mom 26 Sles4 systemic lupus erythmatosus suppressor 4
Mom 26 Bmiq8 body mass index QTL 8
Mom 26 Obq5 obesity QTL 5
Mom 26 Igan3 IgA nephropathy 3
Mom 26 Elnv epilepsy naive
Mom 26 V125Dq7 vitamin D active form serum level QTL 7
Mom 26 V125Dq8 vitamin D active form serum level QTL 8
SB3 10 Mom 21 Obsty3 obesity 3
Mom 21 Sysbp1 systolic blood pressure 1
Mom 21 W3q11 weight 3 weeks QTL 11
  W6q6 weight 6 weeks QTL 6
Mom 21 W10q5 weight 10 weeks QTL 5
Mom 21 Egq7 early growth QTL 7
Mom 21 Hrtq3 heart weight QTL 3
Mom 21 Kidpq2 kidney weight percentage QTL 2
Mom 21 Lvrq4 liver weight QTL 4
Mom 21 Scfpq1 subcutaneous fat pad percentage QTL 1
  Scc9 colon tumor susceptibility 9
  Eae34 experimental allergic encephalomyelitis susceptibility 34
  Lmblgq4 limb length QTL 4
  Lmblgq4 limb length QTL 4
  Angvq1 angiogenesis by VEGF QTL 1
  Phl2 progressive hearing loss 2
  Cia8 collagen induced arthritis QTL 8
  Wght9 weight 9
  Bbaa18 B.burgdorferi-associated arthritis 18
  Skull14 skull morphology 14
  Lmb4 lupus in MRL and B6 F2 cross, QTL 4
  Lifespan2 life span 2
  Pbwg16 postnatal body weight growth 16
  Hpcr2 hepatocarcinogen resistance 2
  Jckm3 juvenile cystic kidney modifier 3
  Ath17 atherosclerosis 17
  Eae17 experimental allergic encephalomyelitis susceptibility 17
  Hfhl4 high-frequency hearing loss 4
  Clfrhl1 click-frequency hearing loss 1
  Lfhl1 low-frequency hearing loss 1
  Mfhl1 medium-frequency hearing loss 1
  Obrq12 obesity resistance QTL 12
  Pcholq4 plasma cholesterol QTL 4
  Gluq1 blood glucose QTL 1
  Bsc1 brain size control 1
  El3 epilepsy 3
  Insq9 insulin QTL 9
  Aem3 anti-erythrocyte autoantibody modifier 3
  Ssrq4 stress response QTL 4
  Pwgrq19 post-weaning growth rate QTL 19
  Tesq3 testis weight QTL 3
  Espq3 embryo survival preimplantation QTL 3
  Estoq3 embryo survival total QTL 3
  Egq9 early growth QTL 9
  Lgaq5 late growth adjusted QTL 5
  W10q8 weight 10 weeks QTL 8
  W6q8 weight 6 weeks QTL 8
  Cia29 collagen induced arthritis QTL 29
  Igf1sl2 IGF-1 serum levels 2
  Ltpr5a Leishmania tropica response 5a
  Ltpr5 Leishmania tropica response 5
  Lgth11 body length 11
  Vtbt9 vertebral trabecular bone trait 9
  Fembrs3 femur breaking strength 3
  Ednrbm1 endothelin receptor type B modifier 1
  Tmevp2 Theiler’s murine encephalomyelitis virus persistence 2
  Ogrq4 overall growth rate QTL 4
  Femwf3 femur work to failure 3
SB3 12   Pifs1 peptide-induced fatal syndrome 1
  Tcq14 total cholesterol QTL 14
  Bmiq11 body mass index QTL 11
  Chldq7 cholesterol and HDL QTL 7
  Tglq5 triglyceride QTL 5
  Femwf9 femur work to failure 9
  Tmc1m3 Tmc1 modifier 3
Total Polyps 16 Mom 23 Eae11 experimental allergic encephalomyelitis susceptibility 11
Mom 22 Arrd3 age-related retinal degeneration 3
Mom 22 / Mom 23 Aod1a autoimmune ovarian dysgenesis 1a
  Tauph tau phosphorylation
Mom 23 Lith14 lithogenic gene 14
Mom 22 Remslp3 rapid eye movement sleep 3
  Etia ethanol induced activation
  Pgia10 proteoglycan induced arthritis 10
  Renf2 renal failure 2
  Sluc27 susceptibility to lung cancer 27
  Bpq9 blood pressure QTL 9
Mom 22 Pcd4ts3 p-glycoprotein positive CD4 T cell subset 3
Mom 22 Ipng3 imprinted postnatal growth 3
  Tgq28 triglyceride QTL 28
Mom 23 Imraq3 immune response to AAV2 QTL 3
Mom 22 / Mom 23 Diobq diet-induced obesity QTL
Mom 22 / Mom 23 Bwtn1 body weight at necropsy 1
Mom 22 Lp1 lymphocyte proliferation 1
Mom 22 / Mom 23 Dice1b determination of interleukin 4 commitment 1b
  Lmr18 leishmaniasis resistance 18
Mom 23 Pod plasticity of ocular dominance
Mom 22 / Mom 23 Eih3 ethanol induced hypothermia 3
Mom 22 / Mom 23 Skts-fp3 skin tumor susceptibility in FVB and PWK 3
  Cocia19 cocaine-induced activity, QTL 19
  Lmr18a leishmaniasis resistance 18a
  Lmr18b leishmaniasis resistance 18b
Mom 22 / Mom 23 Eae41 experimental allergic encephalomyelitis susceptibility 41
Total Polyps 12   Ath6 atherosclerosis 6
  Circp1 circadian photosensitivity 1
  Cplaq10 circadian period of locomotor activity 10
  Pifs1 peptide-induced fatal syndrome 1
  Tcq14 total cholesterol QTL 14
  Bmiq11 body mass index QTL 11
  Chldq7 cholesterol and HDL QTL 7
  Tglq5 triglyceride QTL 5
  Femwf9 femur work to failure 9
  Tmc1m3 Tmc1 modifier 3