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Table 3 Summary of SNVs called and annotated for each species. Total number of samples corresponds to the number of individual WGS and individuals included in each pool (N=4). Fixed SNVs refers to variants calling the alternative allele across all samples in each species relative to the domestic cat

From: Exploiting genomic synteny in Felidae: cross-species genome alignments and SNV discovery can aid conservation management

 

Cheetah

Snow leopard

Sumatran tiger

Quality filtered SNV

 Total

38,839,061

15,504,143

13,414,953

 Coding variants

449,996

144,156

126,127

 Transcripts overlapped

53,786

53,707

53,640

 Genes overlapped

29,043

28,978

28,930

Fixed SNV

 Total

1,737,447

13,882,181

3,755,816

 Coding variants

9,910

122,446

37,539

MAF filtered SNV

 Total

2,671,858

55,604

409,014

 MAF thresholda

0.125

0.25

0.143

 Missense

17,333

623

2,737

 Deleteriousb

4,734

177

772

  1. aMAF thresholds were used to exclude SNV that did not appear in at least one individual in a homozygous state or at least two individuals in a heterozygous state
  2. bSNV annotated as ‘deleterious’ by VEP tool had a SIFT score 0-0.05