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Fig. 3 | BMC Genomics

Fig. 3

From: Altered synthesis of genes associated with short-chain fatty acids in the gut of patients with atrial fibrillation

Fig. 3

Key gut SCFA-related synthesis factors selected by LASSO analysis. (a) Relative abundance levels of the 8 KEGG orthologues (KOs) selected by the least absolute shrinkage and selection operator (LASSO) analysis from different KOs between non-AF controls and AF patients. Log 2 (Odds ratio [OR] score) < 0 (decreased in AF, blue); Log 2 (OR score) > 0 (enriched in non-AF controls, red). (b) Radar plots of the 8 KOs selected by LASSO analysis. Green and purple denote the relative abundance levels of atrial fibrillation (AF) and non-AF controls (CTR), respectively. The outer circle reflects the fold change, with red and blue indicating enrichment in AF and control patients, respectively. (c) Box plot of 2 species selected by LASSO analysis. (d) Formulae of KO, enzyme and species scores obtained by LASSO analysis. (e) Receiver operating curves for KO, enzyme and species scores in AF

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BMC Genomics

ISSN: 1471-2164

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