Table 1 4 gene targets of immune and growth-related functional miRNAs found in the milk samples which are connected to most number of KEGG pathways; the names of some associated signaling pathways have been included. These gene targets have been obtained based on comparing with MirTarBase which is a repository of miRNA-experimentally found gene targets. The differential expression of miRNAs has not been the criteria for tabulating here
miRNA name | Gene name | Name of the KEGG pathway |
|---|---|---|
miR-16a | FOS | MAPK signaling pathway, TNF signaling pathway, cAMP signaling pathway, Apoptosis, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, IL-17 signaling pathway, B cell receptor signaling pathway |
miR-6124, miR-223, miR-520a-3p, miR-6124 | IGF1R | MAPK signaling pathway, HIF-1 signaling pathway, ovarian steroidogenesis, progesterone-mediated oocyte maturation, Ras signaling pathway, Rap1 signaling pathway |
miR-6743-5p | ACTG1 | Hippo signaling pathway, oxytocin signaling pathway, thyroid hormone signaling pathway, |
miR-526b-5p | FZD5 | Wnt signaling pathway, Hippo signaling pathway, mTOR signaling pathway |