Table 1 Genomic region and associated genes of the top 27 significant |iHS|
Chr | Start (bp) | End (bp) | Mean |iHS| Value | No. of SNP | Candidate Genes |
|---|---|---|---|---|---|
6 | 78,000,000 | 78,500,000 | 2.94 | 2 | — |
13 | 34,000,000 | 34,500,000 | 2.88 | 1 | SVIL、ZNF438 |
2 | 92,500,000 | 93,000,000 | 2.68 | 18 | AOX1、AOX2、AOX4、BZW1、CLK1、NIF3L1、ORC2、PPIL3、SGO2 |
13 | 40,000,000 | 40,500,000 | 2.67 | 9 | KIZ |
21 | 28,750,000 | 29,250,000 | 2.66 | 21 | SNRPA1、TARS3、TM2D3 |
14 | 30,750,000 | 31,250,000 | 2.60 | 5 | ARFGEF1、COPS5、CSPP1、PPP1R42、SGK3 |
24 | 20,000,000 | 20,500,000 | 2.55 | 27 | CELF4 |
21 | 29,000,000 | 29,500,000 | 2.53 | 23 | SNRPA1 |
2 | 134,250,000 | 134,750,000 | 2.37 | 1 | CNR2、FUCA1、IFNLR1、IL22RA1、PNRC2、SRSF10 |
24 | 19,750,000 | 20,250,000 | 2.35 | 29 | CELF4 |
5 | 79,000,000 | 79,500,000 | 2.29 | 89 | RBFOX2、LOC515697 |
26 | 2,750,000 | 3,250,000 | 2.29 | 38 | — |
2 | 92,750,000 | 93,250,000 | 2.27 | 22 | AOX2、AOX4、BZW1、CFLAR、CLK1、NDUFB3、NIF3L1、ORC2、PPIL3 |
16 | 39,250,000 | 39,750,000 | 2.24 | 13 | EXOSC10、MASP2、SRM、TARDBP |
22 | 11,000,000 | 11,500,000 | 2.24 | 9 | CTDSPL、ITGA9、MIR2367、MIR26A-1、MIR26C、VILL |
26 | 3,000,000 | 3,500,000 | 2.24 | 39 | — |
8 | 107,500,000 | 108,000,000 | 2.22 | 13 | ALAD、BSPRY、C8H9orf43、CDC26、HDHD3、POLE3、PRPF4、RGS3、RNF183、SLC31A1、SLC31A2 |
1 | 113,500,000 | 114,000,000 | 2.20 | 23 | GMPS、SLC33A1 |
23 | 28,000,000 | 28,500,000 | 2.18 | 8 | MIR12033、OR12D2、UBD |
1 | 147,000,000 | 147,500,000 | 2.15 | 34 | CFAP410、TSPEAR、FAM207A、ITGB2、LRRC3、PFKL、PTTG1IP、UBE2G2、SUMO3、KRTAP10-2、KRTAP10-8、KRTAP12-2、LOC617218、LOC780781 |
8 | 66,500,000 | 67,000,000 | 2.14 | 9 | ALG2、COL15A1、SEC61B、TGFBR1 |
27 | 1,000,000 | 1,500,000 | 2.10 | 16 | CLN8、MYOM2、MIR10169 |
6 | 78,250,000 | 78,750,000 | 2.08 | 4 | — |
19 | 59,750,000 | 60,250,000 | 2.06 | 7 | SLC39A11、SSTR2 |
14 | 58,500,000 | 59,000,000 | 2.03 | 1 | — |
23 | 19,000,000 | 19,500,000 | 2.02 | 16 | SUPT3H |
18 | 10,500,000 | 11,000,000 | 2.00 | 13 | COX4I1、EMC8、IRF8 |