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Fig. 2 | BMC Genomics

Fig. 2

From: Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

Fig. 2

Differential exon usage and functional characterization. A Volcano plot showing changes in exon usage in bovine skeletal muscle exposed in utero to either a control diet (n = 9) or a methionine-rich diet (n = 10). The x-axis shows the magnitude of the change while the y-axis shows the statistical significance of the change. B Six gene annotation databases were analyzed, including Gene Ontology (GO), KEGG, Medical Subject Headings (MeSH), InterPro, Reactome and Molecular Signatures Database. The y-axis displays the term ID and the total number of genes in each functional term. The black dots represent the significance of enrichment (-log10 P-value, Fisher’s exact test, top x-axis) and the bars represent the percentage of significant genes in each functional term (bottom x-axis)

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