Fig. 4

Illustration: Exon expression and DNA methylation in gene PRPF40A. A Exon expression of gene PRPF40A. The x-axis displays the different exons (counting from 5’ to 3’) and the y-axis shows the corresponding expression estimates. B Methylation level of four genomic regions: significant exons, non-significant exons, contiguous introns, non-contiguous introns. Methylation level in a certain genomic region was calculated as differentially methylated cytosines divided by all the evaluated cytosines