Table 1 Top 20 enriched functions for seRNA proximal genes in each state during iPS cell differentiation to neurons. The differentiation process went from cell state k = 0 to k = 2. The q-value was adjusted using Benjamini and Hochberg corrections with ConsensusPathDB. Note that the RNA biosynthetic process or metabolic process related GO terms are marked with @, signal transduction and cellular process related terms with #, development-related terms with ◎, and cellular response related terms with $

# regulation of cellular process

1.3E-12

@ regulation of metabolic process

5.4E-10

◎ cellular developmental process

2.0E-07

@ regulation of RNA metabolic process

3.8E-11

# regulation of cellular process

7.3E-10

# regulation of cellular process

2.0E-07

@ transcription, DNA-templated

3.8E-11

@ negative regulation of cellular metabolic process

3.2E-09

cellular response to chemical stimulus

5.4E-07

@ regulation of nucleobase-containing compound metabolic process

4.4E-11

@ regulation of cellular metabolic process

4.4E-09

◎ multicellular organismal development

5.4E-07

@ RNA biosynthetic process

1.2E-10

@ negative regulation of metabolic process

7.7E-09

◎ cell differentiation

7.4E-07

@ regulation of gene expression

1.3E-10

@ regulation of macromolecule metabolic process

7.7E-09

negative regulation of biological process

5.1E-06

negative regulation of biological process

2.4E-10

@ regulation of primary metabolic process

1.5E-08

◎ system development

9.4E-06

@ regulation of metabolic process

2.4E-10

# negative regulation of cellular process

1.5E-08

◎ cellular response to organic substance

1.3E-05

@ regulation of macromolecule biosynthetic process

4.9E-10

negative regulation of biological process

1.7E-08

regulation of signaling

1.4E-05

$ cellular response to chemical stimulus

5.6E-10

$ cellular response to chemical stimulus

1.7E-08

macromolecular complex subunit organization

2.1E-05

@ regulation of nitrogen compound metabolic process

6.3E-10

@ negative regulation of macromolecule metabolic process

1.7E-08

◎ muscle structure development

5.3E-05

@ regulation of cellular metabolic process

6.3E-10

◎ multicellular organismal development

3.0E-08

# negative regulation of cellular process

7.2E-05

@ regulation of primary metabolic process

8.1E-10

positive regulation of biological process

6.0E-08

positive regulation of biological process

7.7E-05

◎ cell differentiation

8.1E-10

◎ system development

1.3E-07

$ response to organic substance

7.9E-05

@ regulation of biosynthetic process

8.1E-10

$ cellular response to organic substance

2.0E-07

@ regulation of metabolic process

7.9E-05

# positive regulation of cellular process

8.1E-10

◎ tissue development

2.4E-07

@ regulation of RNA metabolic process

9.4E-05

# negative regulation of metabolic process

8.1E-10

@ regulation of cellular component biogenesis

4.6E-07

@ transcription, DNA-templated

9.4E-05

@ regulation of macromolecule metabolic process

8.2E-10

@ regulation of gene expression

5.0E-07

@ regulation of nucleobase-containing compound metabolic process

9.4E-05

positive regulation of biological process

8.8E-10

◎ cellular developmental process

7.9E-07

@ regulation of macromolecule biosynthetic process

9.4E-05

◎ cellular developmental process

8.8E-10

# positive regulation of cellular process

1.0E-06

regulation of gene expression

1.0E-04