Genetic association tests in family samples for multi-category phenotypes

BMC Genomics

Table 2 Simulation results of type-I error for unrelated samples

MAF	Score test		Wald test		Logistic regression (LRT)
MAF	α = 0.01	α = 0.001	α = 0.01	α = 0.001	α = 0.01	α = 0.001
0.01	0.011	0.0010	0.008	0.0006	0.011	0.0011
0.02	0.010	0.0016	0.010	0.0016	0.012	0.0014
0.03	0.012	0.0012	0.011	0.0010	0.011	0.0014
0.04	0.011	0.0010	0.010	0.0010	0.011	0.0010
0.05	0.010	0.0010	0.006	0.0004	0.010	0.0005
0.1	0.010	0.0010	0.010	0.0008	0.010	0.0010
0.2	0.010	0.0010	0.009	0.0004	0.010	0.0010
0.3	0.009	0.0011	0.009	0.0006	0.010	0.0010

ISSN: 1471-2164