Table 5 Power results for unrelated samples
From: Genetic association tests in family samples for multi-category phenotypes
MAF | α=0.01 | α=0.001 | α = 5 × 10−8 | |||
|---|---|---|---|---|---|---|
0.01 | score | 95.0 | score | 85.8 | score | 26.5 |
Wald | 94.1 | Wald | 82.8 | Wald | 15.6 | |
Logistic (LRT) | 92.9 | Logistic (LRT) | 79.6 | Logistic (LRT) | 11.4 | |
0.02 | score | 93.3 | score | 82.3 | score | 20.0 |
Wald | 92.8 | Wald | 80.6 | Wald | 14.6 | |
Logistic (LRT) | 91.6 | Logistic (LRT) | 77.4 | Logistic (LRT) | 10.6 | |
0.03 | score | 92.7 | score | 81.1 | score | 15.9 |
Wald | 92.4 | Wald | 79.5 | Wald | 12.7 | |
Logistic (LRT) | 91.2 | Logistic (LRT) | 76.8 | Logistic (LRT) | 9.5 | |
0.04 | score | 92.4 | score | 79.2 | score | 14.1 |
Wald | 92.0 | Wald | 78.2 | Wald | 11.3 | |
Logistic (LRT) | 90.8 | Logistic (LRT) | 75.4 | Logistic (LRT) | 8.6 | |
0.05 | score | 92.0 | score | 77.9 | score | 13.1 |
Wald | 91.9 | Wald | 77.3 | Wald | 10.9 | |
Logistic (LRT) | 90.9 | Logistic (LRT) | 74.7 | Logistic (LRT) | 8.2 | |
0.1 | score | 91.3 | score | 75.7 | score | 10.4 |
Wald | 91.0 | Wald | 74.9 | Wald | 9.5 | |
Logistic (LRT) | 90.3 | Logistic (LRT) | 73.2 | Logistic (LRT) | 7.8 | |
0.2 | score | 89.9 | score | 73.2 | score | 8.1 |
Wald | 89.7 | Wald | 73.0 | Wald | 7.5 | |
Logistic (LRT) | 89.3 | Logistic (LRT) | 71.9 | Logistic (LRT) | 6.8 | |
0.3 | score | 89.2 | score | 72.2 | score | 7.0 |
Wald | 89.3 | Wald | 71.8 | Wald | 6.5 | |
Logistic (LRT) | 89.0 | Logistic (LRT) | 71.5 | Logistic (LRT) | 6.3 | |