Table 2 Sets of core-fitness and common-essential genes obtained by novel analyses of the DepMap dataset and considered to benchmark CoRe
Set name | Set Type | Number of genes | Dataset of origin |
|---|---|---|---|
CEN-tools | Novel analysis | 756 [For the comparison with the unsupervised methods, this set was joined with the curated Hart2014 set (used in its training phase), rising up to 1082 genes] | DepMap dataset [19]. |
CoRe ADaM | Novel analysis | 1075 | DepMap dataset [19] |
CoRe FiPer average | Novel analysis | 1424 | DepMap dataset [19] |
CoRe FiPer slope | Novel analysis | 1704 | DepMap dataset [19] |
CoRe FiPer AUC | Novel analysis | 1987 | DepMap dataset [19] |
CoRe FiPer Fixed | Novel analysis | 1947 | DepMap dataset [19] |
CoRe FiPer consensus | Novel analysis | 1673 | DepMap dataset [19] |