Table 4 Mutation rates of simulated samples of rs28934573 (C > T)
Mixture Ratio | Theoretical value | Mean | Repeat 1 | Repeat 2 | Repeat 3 | Variance | CV |
|---|---|---|---|---|---|---|---|
HCT-15 | 50.00% | 50.64% | 51.04% | 49.52% | 51.37% | 0.99% | 1.95% |
HaCaT | 0.00% | 0.11% | 0.13% | 0.10% | 0.10% | 0.02% | 15.75% |
50% HCT-15/HaCaT | 16.67% | 17.42% | 16.59% | 17.80% | 17.87% | 0.72% | 4.13% |
25% HCT-15/HaCaT | 10.00% | 11.04% | 11.86% | 10.89% | 10.37% | 0.76% | 6.85% |
10% HCT-15/HaCaT | 4.55% | 5.34% | 5.25% | 5.75% | 5.03% | 0.37% | 6.91% |
5% HCT-15/HaCaT | 2.38% | 2.82% | 2.50% | 2.48% | 3.47% | 0.57% | 20.09% |
1% HCT-15/HaCaT | 0.50% | 0.63% | 0.68% | 0.37% | 0.84% | 0.24% | 37.93% |
0.5% HCT-15/HaCaT | 0.25% | 0.24% | 0.25% | 0.29% | 0.19% | 0.05% | 20.68% |
0.1% HCT-15/HaCaT | 0.05% | 0.16% | 0.09% | 0.30% | 0.10% | 0.12% | 72.53% |