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Table 2 NFATc1 target gene regulation prediction based on the regulation prediction using SVM, NN and log2FC only

From: Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP

Model Up regulation Down regulation
Log2FC only ABCB4, ACADM, ACADS, ACADVL, ACAT1, ACBD6, ACO2, AK2, ALDH4A1, AP1G2, APBA3, ATP5E, ATP5G1, ATP5G2, ATP5G3, ATP5J, ATP5L, ATP6V0B, ATP6V1C1, ATP6V1D, ATP6V1H, BCAT2, BCL2L13, BSG, C1QBP, CIAPIN1, COMTD1, COQ6, COX15, COX5B, COX7A2, COX7A2L, CS, CTTN, CYC1, CYCS, DLAT, DLST, ECSIT, ETFA, ETFDH, EXT1, FAHD1, FASTK, FDXR, GNB1L, GPX4, GSS, GTF2H3, HAGH, HINT3, IDH3A, IDH3B, IK, IMMT, KIF13A, LETM1, LRPPRC, MANBAL, MCAT, MCRS1, MDH1, MDH2, MFN2, MRPL1, MRPL14, MRPL34, MRPL36, MRPL38, MRPL46, MRPL48, MRPL51, MRPL9, MRPS25, MRPS34, MRPS35, MTX2, NDUFA10, NDUFA4, NDUFA5, NDUFA6, NDUFAB1, NDUFAF1, NDUFB10, NDUFB3, NDUFB5, NDUFB6, NDUFB7, NDUFC1, NDUFS3, NDUFS7, NDUFS8, NHEJ1, NSMAF, NUDT8, OGDH, OPA1, OXNAD1, PABPC4, PGAM5, PGLS, PIGO, PIP5K1B, PITPNM1, PPA2, PPARGC1B, PTGES2, PTPN12, PTPN9, RABGEF1, RELB, REPIN1, RREB1, SDHD, SLC25A11, SLC25A19, SLC25A3, SLC25A39, SLC25A5, SLC30A6, SLC39A13, SOD2, ST5, STARD7, TANK, TARBP2, TAX1BP3, TBC1D10B, TBRG4, TCIRG1, TERF2IP, TFRC, TIMM17A, TIMM44, TMEM60, TNFAIP3, TTC19, TUFM, UBE2G1, UBLCP1, UQCRC1, UQCRC2, UQCRH, USP4, VDAC1, VTI1B CD164, CD48, CHST12, CNR2, CORO1A, EBI3, EPS15, FLI1, GCA, GNG2, IER3, IL10RA, IRF8, LAMP1, LSP1, MARCKS, NEDD9, NUCB2, P2RY6, PKIB, POU2F2, PRKD2, RASSF5, RB1, RBM43, RNASE4, RPS6KA3, SSBP2, TLE3, TLR6, TNFSF9, TPD52, WSB1, ZFP90
SVM ABCB4, ACAD10, ACADS, AP1G2, ATP5L, CIAPIN1, CNIH4, COX15, COX7A2, CYC1, DLAT, DNAJA3, DUS3L, EXT1, FAHD1, FDXR, FEM1A, HAGH, HINT3, IDH3A, IMMT, LRPPRC, MANBAL, MCAT, MCRS1, MRPL36, MRPL38, MRPL9, MRPS34, MRPS35, NDUFB10, NDUFB5, NDUFB6, NDUFS3, NDUFS7, NSMAF, PABPC4, PEX16, PGLS, PIGQ, PIP5K1B, PPARGC1B, PRDX3, PTGES2, PTPN12, SEMA7A, SLC25A19, SLC39A13, SSNA1, ST5, TIMM44, TTC19, TUFM, USP4 ANXA6, ATF3, CCL3, CD48, CDC42EP3, CHST12, CPEB2, DCK, EBI3, FLI1, GNG2, IRF5, IRF8, LSP1, LXN, MAP4K2, PIK3CG, SLC15A3, SLC9A3R1, SP100, TEX2, TLR6, TNFSF9, ZFP90
NN ABCB4, ACAD10, ACADS, AK2, AP1G2, ATP5G3, ATP5L, BCAT2, CIAPIN1, COG8, COQ6, COX15, COX17, CYC1, DLAT, DNAJA3, DUS3L, ECSIT, ETFDH, EXT1, FASTK, FDXR, GSS, HAGH, HINT2, HINT3, IDH3A, LRPPRC, MANBAL, MBTPS1, MCRS1, MRPL12, MRPL38, MRPL9, MRPS25, MRPS34, MRPS35, NDUFB10, NDUFC1, NDUFS3, NDUFS7, NSMAF, NUDT8, OXNAD1, PABPC4, PIP5K1B, PITPNM1, PPARGC1B, PRDX3, PTDSS2, PTGES2, RABGEF1, RELB, SLC39A13, STARD7, TANK, TAX1BP3, TBRG4, TCF12, TTC19, TUFM, UBE2G1, UBLCP1, UMPS, USP4 ADAM15, CCL3, CD48, CHST12, CPEB2, EBI3, FLI1, GNG2, IL10RA, IRF8, LSP1, LXN, MAP4K2, MARCKS, MS4A7, NAB2, NOTCH1, NUCB2, P2RY6, POU2F2, RB1, RNASE4, RPS6KA3, SLC15A3, SLC9A3R1, SNAP29, TEX2, TMBIM1, TNFSF9
Gaussian NB ACO2, ACSL1, DLAT, DNAJA3, FDXR, GSS, MCRS1, NFKB2, NFKBIE, NUDT8, OTUD7B, OXNAD1, PPARGC1B, PTGES2, SARS2, SDC1, SEMA7A, SLC25A39, SLC39A13, TARBP2, TBRG4, TRAF1 CCR5, CDC42EP3, CNR2, ECE1, GSTK1, ICAM2, NAB2, PIAS3, SORL1, TLR6, TNFSF9
LR ABCB4, ACAD10, AK2, AP1G2, ATOX1, ATP5G2, BCAT2, DNAJA3, DUS3L, EXT1, FAHD1, FASTK, FDXR, IDH3A, IVNS1ABP, MCRS1, MFN2, NDUFS3, NFKBIE, NSMAF, OTUD7B, OXNAD1, PABPC4, PPARGC1B, PTGES2, PTPN12, REPIN1, SDC1, SEMA7A, SERPINB8, SLC39A13, ST5, STARD7, TANK, TARBP2, TBRG4, XRCC5 GSTK1, HSPA2, ICAM2, NFKBIZ, PARVG, RASSF5, RBM43, SORL1, TNFSF9