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Table 2 Norepinephrine enhanced expression of genes encoding various stress-related pathways

From: Genomewide transcriptional response of Escherichia coli O157:H7 to norepinephrine

Pathway/Gene groupa

Locus Tag

Geneb

Gene function

Fold

changec

p adjusted

Stress/cell division/biofilms

     
 

BHW77_19325

dps

DNA starvation/stationary phase protection protein Dps

+2.88

5.77E-04

 

BHW77_01455

uspB

universal stress protein UspB

+3.07

1.96E-03

 

BHW77_14630

uspF

universal stress protein F

+2.01

3.42E-04

 

BHW77_20660

uspG

universal stress protein UspG

+2.76

3.62E-04

 

BHW77_18490

hspQ

heat-shock protein HspQ

+2.29

1.12E-03

 

BHW77_00060

ibpA

heat-shock protein

+2.15

2.84E-02

 

BHW77_10075

cspG

cold-shock protein

+2.99

2.31E-06

 

BHW77_06270

clpB

ATP-dependent chaperone ClpB

+2.72

3.11E-03

 

BHW77_02235

fic-1

cell filamentation protein

+2.95

8.37E-04

 

BHW77_18535

sulA

cell division inhibitor

+1.80

8.47E-04

 

BHW77_19955

cpoB

cell division protein

−2.61

2.01E-07

 

BHW77_18715

mukB

cell division protein

−2.12

6.72E-08

 

BHW77_14120

dosC

diguanylate cyclase

+2.87

3.86E-08

 

BHW77_21465

bolA

transcriptional regulator

+3.22

2.57E-05

 

BHW77_19190

bssR

transcriptional regulator

+2.76

1.25E-04

 

BHW77_11525

bssS

transcriptional regulator

+7.75

4.94E-08

 

BHW77_17570

flhC

transcriptional regulator

−1.62

2.44E-02

 

BHW77_16255

sodC

superoxide dismutase

+ 2.81

3.37E-04

  1. aGene group/gene designations were selected from RAST Server [109]
  2. bGene name and known or predicted functions are based on the annotated sequence of E. coli O157:H7 EDL 933 [110]
  3. c + Symbol represents that the gene expression listed in the column was upregulated