Table 4 Differential expression of various metabolic pathways in response to norepinephrine

Amino acid ABC transport

3

3’,5’-cyclic-AMP phosphodiesterase

1

Amino acid transport

2

30S ribosomal proteins

11

23S and 16S rRNA methylation

4

50S ribosomal proteins

17

Anaerobic ribonucleotide reductase and dehydrogenase

2

6-phosphofructokinase II

1

Cell division/cell division inhibition

4/1

ABC transporter ATP-binding

protein

2

Cytochrome oxidase

1

ABC transporter permease

2

Diguanylate cyclase/phosphoesterase

1/1

Acetate-CoA ligase

1

DNA replication, modification and repair

7

Acetolactate synthase

4

DUF domain containing proteins

21

Acetyl-CoA transferase/carboxylase

1/3

Ferrous ion transport

3

Adenine uptake/utilization

5

Glutamate metabolism

5

Alanine utilization

4

Glutamine ABC transport

3

Alcohol/Aldehyde dehydrogenase

1/1

Glycogen synthesis

1

Aldolase

1

Hypothetical proteins

87

Aspartate metabolism

6

Integrases/transposases

8/12

ATP F0F1 synthase subunit C

LPS biosynthesis

4

C4-dicarboxylate transporter

Multidrug ABC transport/efflux

2/2

Bifunctional aspartate kinase, cysteine desulfurase, glutamine synthase

3

Multidrug transport

6

Enterobactin biosynthesis

2

NAD(P)-dependent oxidoreductases

3

Cell division proteins

8

Nitrate/nitrite transport

3

Citrate metabolism

2

Nitrate/nitrite reductases

2/2

Cytochrome b

2

Outer membrane proteins

4

Cytochrome c biogenesis protein

2

Oxidoreductases

6

Cytochrome O ubiquinol oxidase

4

Pyrimidine utilization proteins

5

Cytosine metabolism

2

Sugar fermentation stimulation protein

1

Dipeptide ABC transport

4

Sugar transporter

1

Electron transport complex subunit

RsxD, E, and G

3

Sulfate/sulfite transport metabolism

9

F0F1 ATP synthase

7

Zn transport

PTS fructose transporter

2

1

Fe2+ -enterobactin and Fe³⁺-hydroxamate ABC transport proteins

2

Ferredoxin reductase

2

Fe-S cluster assembly proteins

6

Formate dehydrogenase

5

Fructose biphosphate

1

Galactose metabolism

3

Glucan biosynthesis

2

Glutathione metabolism

6

Glycerol metabolism

4

Glycine metabolism

5

Heme/hemen transport and utilization

4

Branched-chain amino acid transport

2

Hypothetical proteins

101

Iron ABC transporter

1

Iron-enterobactin and iron-hydroxamate transport

4

Isochorismate/isochorismate synthase EntC

2

LPS biosynthesis

3

Microcin transport

3

Molybdate transport and molybdenum cofactor biosynthesis

6

Multidrug transporter MdtBCDJ

4

Multifunctional acyl-CoA and fatty acid oxidation complex

3

Murein biosynthesis

9

NAD(P)-dependent, NAD, NADH and NADHP- dependent enzymes

14

Nitric oxide dioxygenase and reducatse

2

Oxidative damage protection protein/defense proteins

1/1

Peptide ABC transport

2

Peptidylprolyl isomerases (proper protein -folding)

5

Phage shock proteins (PspBDA)

3

Phosphate transport

6

Phosphoenolpyruvate--protein phosphotransferase

2

phosphoethanolamine transferase

1

phosphoribosylamine-glycine ligase and 5 other enzymes of purine biosynthesis

6

Preprotein translocase subunits SecY, SecA, YajC, YidC

4

Protein-export membrane protein SecD, SecF

PTS glucose/sugar transporter

1/1

Putrescine/Spermidine ABC transporters

1/1

pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase

1

Pyruvate Kinase

2

Serine metabolism

2

Spermidine/putrescine metabolism

2

Succinate dehydrogenase

7

Tellurite resistance proteins

7

Thiamine ABC transport

2

Threonine synthase

1

Thymidylate synthase

1

Transcriptional regulator FlhC

1

Translation elongation factors G, Ts, Tu, Tu, IF-2, IF-3

6

Transposase

2

tRNA modification enzyme complexes

11

Tryptophanase

1

Type II secretion system

6

Tyrosine-protein kinase

1

UDP-N-acetylglucosamine and UDP-N-acetylmuramate-amino acid ligases (cell wall biosynthesis)

9

Urease accessory proteins and subunits α, β, γ

7