Fig. 1
From: Genetic architecture of protein expression and its regulation in the mouse brain
Schematic diagram of the experimental design and data analysis of this study. A Experimental scheme. Four strains, including B6, D2, and the two reciprocal F1s (B6D2F1 and D2B6F1), were used. B Mouse brain proteome was profiled by TMT-based proteomics, followed by data quality control and differential expression analysis. C Genetic variance analysis. D Allele-specific expression was defined by the proteogenomics approach. E Regulations at the transcript and protein levels were compared