Table 1 Significantly enriched KEGG pathways in the M_IIIvsM_IV and M_IVvsM_V groups
Stage | KEGG pathway | ID | Input gene | Regulation |
|---|---|---|---|---|
M_IIIvsM_IV | ||||
Intercellular interaction and cytoskeleton | ECM-receptor interaction | ko04512 | 39 | DOWN |
Focal adhesion | ko04510 | 64 | DOWN | |
Regulation of actin cytoskeleton | ko04810 | 59 | DOWN | |
Molecule amplification and repair in the cell cycle | Cell cycle | ko04110 | 39 | UP |
Ubiquitin-mediated proteolysis | ko04120 | 27 | UP | |
DNA replication | ko03030 | 10 | UP | |
Fanconi anemia pathway | ko03460 | 12 | UP | |
mRNA surveillance pathway | ko03015 | 23 | UP | |
Steroid hormone biosynthesis | ko00140 | 21 | DOWN | |
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | ko00563 | 7 | UP | |
M_IVvsM_V | ||||
Progesterone- induced gamete maturation | Progesterone-mediated oocyte maturation | ko04914 | 117 | UP |
Oocyte meiosis | ko04114 | 129 | UP | |
Molecule amplification and repair in the cell cycle | mRNA surveillance pathway | ko03015 | 97 | UP |
Cell cycle | ko04110 | 140 | UP | |
Ubiquitin-mediated proteolysis | ko04120 | 143 | UP | |
RNA transport | ko03013 | 139 | UP | |
p53 signaling pathway | ko04115 | 69 | UP | |
Apoptosis - multiple species | ko04215 | 34 | UP | |
Endoplasmic reticulum-related protein processing and exocytosis in nervous system | Protein processing in endoplasmic reticulum | ko04141 | 159 | UP |
Synaptic vesicle cycle | ko04721 | 102 | UP | |
Retrograde endocannabinoid signaling | ko04723 | 179 | UP | |
Infection- and immune-related | Staphylococcus aureus infection | ko05150 | 49 | DOWN |
Transcriptional misregulation in cancer | ko05202 | 174 | DOWN | |
Pertussis | ko05133 | 73 | DOWN | |
RNA transport | ko03013 | 30 | DOWN | |
Huntington’s disease | ko05016 | 205 | UP |