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Fig. 4 | BMC Genomics

Fig. 4

From: Nuclear transport genes recurrently duplicate by means of RNA intermediates in Drosophila but not in other insects

Fig. 4

Proposed model of how the piRNA pathway might be involved in the SD system in Drosophila. piRNA precursors are exported from the nucleus to the cytoplasm, where piRNA biogenesis and loading of the RNA to the Piwi protein happens. Import of this complex to the nucleus has been proposed to be needed for chromatin condensation of the Rsp repeats and in SD it might not occur due to disruption of Ran-GTP/Ran-GDP gradient [28, 33, 34]

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