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Table 4 Immunogenic potential of all proteins in genomes of virulent and commensal strains of C. perfringens analyzed

From: Putative antigenic proteins identified by comparative and subtractive reverse vaccinology in necrotic enteritis-causing Clostridium perfringens isolated from broiler chickens

Strain type

Strain identification

No. of proteins/genome

% of genome identified as antigenic

No. of proteins as probable and improbable antigen

No. of proteins for each immunogenicity score category

Improbable antigen [score < 0,5]

Probable antigen [score > 0,5]

[0,5-0,7]

[0,7-0,9]

[0,9-1,5]

> 1,5

Virulent

MLG_2313

3351

33,24%

2237

1114

879

192

42

0

MLG_2514

3065

34,26%

2015

1050

812

182

54

2

MLG_1202

3646

34,20%

2399

1247

979

210

56

2

MLG_2915

3255

33,79%

2155

1100

845

190

64

1

MLG_7814

3556

34,06%

2345

1211

955

199

55

2

MLG_7820

3465

33,68%

2298

1167

906

202

56

3

 

Average

3390

33,87%

2242

1148

896

196

55

2

Commensal

MLG_5806

3002

32,31%

2032

970

788

146

35

1

MLG_4206

3086

32,73%

2076

1010

819

149

42

0

MLG_3406

3091

32,68%

2081

1010

817

147

46

0

MLG_5213

3344

33,07%

2238

1106

883

181

42

0

MLG_0612

3328

33,02%

2229

1099

883

176

40

0

MLG_3119

3093

31,49%

2119

974

786

149

40

0

MLG_2919

3092

31,47%

2119

973

784

148

41

0

MLG_2719

3094

31,45%

2121

973

783

149

41

0

MLG_2019

2916

32,30%

1974

942

763

741

38

0

MLG_1619

2944

32,17%

1997

947

771

137

39

0

 

Average

3099

32,27%

2099

1000

808

212

40

0,1