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Fig. 4 | BMC Genomics

Fig. 4

From: Computational modeling of chromatin accessibility identified important epigenomic regulators

Fig. 4

H2AZ.1 serves as major histone modifications in chromatin accessibility regulation. A and B. Boxplots indicating the H2AZ.1 signal difference in ACRs and non-ACRs. P value was calculated by Wilcoxon rank sum test. ACRs and non-ACRs were 2000 randomly chosen bins from the total ACRs and non-ACRs. C. ROC curves of using H2AZ.1 as feature for chromatin accessibility prediction in GM12878 and HepG2 cell lines. AUCs were calculated by taking the taking the average AUC of 10-folds cross validation. D. Heatmap showing the correlation between H2AZ.1 signals and other HM signals. The correlation coefficient was calculated by Spearman Correlation

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