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Fig. 8 | BMC Genomics

Fig. 8

From: Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System

Fig. 8

Gene Ontologies (Metascape [116]) for genes exhibiting increased CpG-DMRs after SCI in tadpole (CNS axon regenerative) hindbrain. The twenty highest ranking categories (i.e., lowest probability (P) of arising by chance) are listed separately for up-regulated (top) and down-regulated (bottom) genes. Up-regulated genes were highly enriched for categories representing genes associated with DNA replication, repair, and covalent modification (red boxes). Injury-induced genes that decreased in expression had many genes associated with physiological functions and developmental functions (see text). Total numbers of genes in the top and bottom panels were 738 and 460, respectively

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BMC Genomics

ISSN: 1471-2164

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