Table 4 The significant SNPs for concentrations of total IgG, IgG1, IgG2, IgA and IgM in serum

ser_IgG

3

BovineHD0300032641

112,978,010

A/C

0.20

−0.18

0.04

6.12E-05

ser_IgG

3

BovineHD0300032649

113,013,960

A/G

0.20

−0.18

0.04

6.06E-05

ser_IgG

3

BovineHD0300032659

113,046,130

G/A

0.18

−0.20

0.05

1.31E-05

ser_IgG

6

ARS-BFGL-NGS-100863

54,826,213

G/A

0.26

0.17

0.04

1.10E-05

ser_IgG

6

BovineHD0600015431

56,407,206

G/A

0.21

0.17

0.04

5.20E-05

ser_IgG

6

BovineHD0600015455

56,506,982

G/A

0.20

0.17

0.04

5.55E-05

ser_IgG

22

ARS-BFGL-NGS-111049

46,902,036

G/A

0.35

0.15

0.04

3.38E-05

ser_IgG

30

BovineHD3000006683

20,390,212

A/G

0.40

0.16

0.04

1.39E-05

ser_IgG1

9

BovineHD0900016412

59,785,726

G/A

0.26

0.10

0.02

3.08E-05

ser_IgG1

19

BovineHD1900006278

21,930,663

A/G

0.27

−0.10

0.02

1.31E-05

ser_IgG2

7

BovineHD0700004317

15,718,585

G/A

0.47

0.20

0.05

4.79E-05

ser_IgG2

12

BovineHD1200006401

21,324,076

G/A

0.37

0.22

0.06

6.06E-05

ser_IgG2

12

BovineHD1200008568

28,980,452

C/A

0.34

0.24

0.06

4.55E-05

ser_IgG2

12

BovineHD1200024367

84,101,237

A/G

0.48

0.21

0.05

5.80E-05

ser_IgG2

20

BovineHD2000021006

71,896,856

G/A

0.28

0.47

0.06

1.01E-14

ser_IgG2

21

BovineHD2100018564

63,334,736

A/C

0.41

−0.24

0.06

2.10E-05

ser_IgG2

21

BovineHD2100018787

63,926,754

G/A

0.47

−0.26

0.05

1.21E-06

ser_IgG2

21

BovineHD2100018795

63,954,059

G/A

0.35

0.24

0.06

1.89E-05

ser_IgG2

21

BTA-24891-no-rs

63,955,841

G/A

0.36

0.24

0.05

9.73E-06

ser_IgG2

21

BovineHD2100019235

65,578,768

A/G

0.48

−0.23

0.05

1.49E-05

ser_IgG2

21

BovineHD2100019547

66,578,213

A/G

0.40

−0.24

0.05

1.11E-05

ser_IgG2

21

BovineHD2100019656

66,910,728

G/A

0.42

0.28

0.05

2.64E-07

ser_IgG2

21

BovineHD2100019670

66,973,587

A/C

0.39

0.28

0.06

5.53E-07

ser_IgG2

21

ARS-BFGL-NGS-37313

66,988,787

C/A

0.40

0.26

0.05

2.58E-06

ser_IgG2

21

BovineHD2100019681

67,009,668

A/G

0.40

0.26

0.05

1.65E-06

ser_IgG2

21

ARS-BFGL-NGS-107488

67,030,857

A/G

0.31

−0.24

0.06

2.07E-05

ser_IgG2

21

ARS-BFGL-NGS-20339

67,088,847

G/A

0.33

0.26

0.06

2.57E-06

ser_IgG2

21

BovineHD2100019763

67,342,472

C/A

0.44

0.25

0.06

8.91E-06

ser_IgG2

21

BovineHD2100019814

67,542,721

A/C

0.36

0.31

0.06

3.08E-08

ser_IgG2

21

BovineHD2100019834

67,604,077

A/C

0.15

0.33

0.08

1.60E-05

ser_IgG2

21

BovineHD2100019854

67,706,221

G/A

0.30

−0.25

0.06

1.85E-05

ser_IgG2

21

BovineHD4100015366

67,786,313

A/G

0.42

0.31

0.06

2.07E-08

ser_IgG2

21

BovineHD2100019888

67,885,290

A/G

0.21

0.29

0.06

4.33E-06

ser_IgG2

21

BovineHD2100019906

67,946,189

A/G

0.32

0.27

0.06

3.43E-06

ser_IgG2

21

ARS-BFGL-NGS-86477

68,399,787

A/C

0.48

−0.27

0.06

1.11E-06

ser_IgG2

21

BovineHD2100020097

68,740,864

G/A

0.30

0.25

0.06

1.68E-05

ser_IgG2

21

BovineHD2100020157

69,009,950

A/C

0.44

0.27

0.05

1.05E-06

ser_IgG2

21

BovineHD2100021033

69,033,145

G/A

0.20

0.38

0.07

8.11E-09

ser_IgG2

21

BovineHD2100020203

69,206,894

G/A

0.33

−0.23

0.06

3.77E-05

ser_IgG2

21

BovineHD2100020225

69,289,258

A/G

0.33

0.31

0.05

1.15E-08

ser_IgG2

21

BovineHD2100020232

69,327,116

G/A

0.35

0.32

0.05

4.36E-09

ser_IgG2

21

BovineHD2100020241

69,357,379

A/C

0.42

0.25

0.06

4.78E-06

ser_IgG2

21

ARS-BFGL-NGS-115062

69,395,154

G/A

0.44

0.26

0.06

2.21E-06

ser_IgG2

21

BovineHD2100020269

69,440,566

A/G

0.29

−0.25

0.06

4.16E-05

ser_IgG2

21

BovineHD2100020314

69,587,749

G/A

0.36

−0.24

0.05

1.51E-05

ser_IgG2

21

BovineHD2100020317

69,613,677

G/A

0.24

0.28

0.06

1.47E-05

ser_IgG2

21

BovineHD2100020325

69,637,166

A/G

0.36

−0.23

0.05

3.79E-05

ser_IgG2

21

BovineHD2100020341

69,673,486

A/G

0.36

0.34

0.05

1.78E-10

ser_IgG2

21

BovineHD2100020413

69,920,970

G/A

0.38

0.30

0.05

5.65E-08

ser_IgG2

21

ARS-BFGL-NGS-1345

69,939,350

C/A

0.42

0.26

0.05

1.47E-06

ser_IgG2

21

BovineHD2100020425

69,955,674

G/A

0.45

0.24

0.05

1.55E-05

ser_IgG2

21

BovineHD2100020439

70,000,656

A/G

0.45

0.27

0.06

1.66E-06

ser_IgG2

21

ARS-USDA-AGIL-chr21–70,182,028-000470

70,182,028

C/G

0.38

0.23

0.05

2.74E-05

ser_IgG2

21

BovineHD2100020583

70,430,736

G/A

0.23

0.29

0.06

4.23E-06

ser_IgG2

21

BovineHD2100020653

70,537,404

A/G

0.18

0.38

0.07

1.09E-08

ser_IgG2

21

BovineHD2100020670

70,592,463

A/C

0.41

0.29

0.05

1.38E-07

ser_IgG2

21

ARS-BFGL-NGS-2644

70,608,408

A/G

0.35

0.38

0.06

3.24E-11

ser_IgG2

21

BovineHD2100020676

70,621,565

G/A

0.35

0.39

0.06

8.11E-12

ser_IgG2

21

BovineHD2100020685

70,655,075

A/G

0.32

0.39

0.06

2.23E-11

ser_IgG2

21

BovineHD2100020689

70,672,433

A/G

0.38

0.29

0.06

3.46E-07

ser_IgG2

21

BovineHD2100020696

70,687,439

G/A

0.37

0.32

0.05

2.50E-09

ser_IgG2

21

ARS-BFGL-NGS-73522

70,702,245

G/A

0.35

0.32

0.06

1.25E-08

ser_IgG2

21

Hapmap54369-rs29015082

71,109,676

A/G

0.45

−0.22

0.05

3.52E-05

ser_IgG2

21

BovineHD2100020833

71,318,798

A/G

0.29

0.32

0.06

4.01E-08

ser_IgG2

21

BovineHD2100020847

71,359,883

A/G

0.14

0.33

0.08

1.72E-05

ser_IgG2

21

BovineHD2100020883

71,479,429

A/G

0.16

0.43

0.07

2.43E-09

ser_IgA

15

BTA-91367-no-rs

60,316,301

A/G

0.47

−0.11

0.03

2.13E-05

ser_IgM

6

BovineHD0600009523

34,015,077

G/A

0.28

−0.11

0.02

5.25E-06

ser_IgM

6

BovineHD0600014163

51,369,747

G/A

0.12

−0.14

0.03

4.59E-05

ser_IgM

7

ARS-BFGL-NGS-12159

19,220,954

A/C

0.44

−0.09

0.02

4.98E-05

ser_IgM

17

BovineHD1700021706

74,223,510

G/A

0.17

−0.12

0.03

2.79E-05