Genome-wide association studies for immunoglobulin concentrations in colostrum and serum in Chinese Holstein

BMC Genomics

Table 5 The list of candidate genes contained or nearby the significant SNPs associated with total IgG, IgG1, IgG2, IgA and IgM in the colostrum and serum

Gene ID	Gene Name	Chr^a	Gene Start^b	Gene End^b	Traits
ENSBTAG00000010543	FGFR4	18	39,936,163	39,946,911	col_IgG
ENSBTAG00000014064	FGFR2	18	41,823,602	41,930,655	col_IgG
ENSBTAG00000003305	NCF1	11	33,267,455	33,282,333	col_IgG1
ENSBTAG00000006268	IKBKG	11	40,501,901	40,519,263	col_IgG1
ENSBTAG00000014401	SORBS3	21	70,357,692	70,384,760	col_IgG2, ser_IgG2
ENSBTAG00000053635	IGHV1S18	21	71,529,984	71,530,481	col_IgG2, ser_IgG2
ENSBTAG00000002699	KIT	21	71,796,317	71,917,430	col_IgG2, ser_IgG2
ENSBTAG00000014127	PTGS2	10	69,263,775	69,271,399	col_IgM
ENSBTAG00000013340	BAX	6	55,985,201	55,989,210	ser_IgG
ENSBTAG00000004736	GRB2	6	56,754,111	56,818,428	ser_IgG
ENSBTAG00000000827	TAOK1	19	21,308,164	21,363,337	ser_IgG1
ENSBTAG00000010303	ICAM1	7	16,040,883	16,051,454	ser_IgG2
ENSBTAG00000020457	TGFB1	6	50,772,077	50,785,924	ser_IgM
ENSBTAG00000022927	RAC3	6	51,470,005	51,471,808	ser_IgM

^aCow chromosome number
^bThe position of gene was based on the UMD 3.1 assembly
col_IgG, col_IgG1, col_IgG2, col_IgA and col_IgM represented concentration of total IgG, IgG1 IgG2, IgA and IgM in colostrum; ser_IgG, ser_IgG1, ser_IgG2, ser_IgA and ser_IgM represented concentration of total IgG, IgG1 IgG2, IgA and IgM in serum

ISSN: 1471-2164