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Fig. 5 | BMC Genomics

Fig. 5

From: Combined PD-1/PD-L1 and tumor-infiltrating immune cells redefined a unique molecular subtype of high-grade serous ovarian carcinoma

Fig. 5

Differential clinicopathological features and survival of HGSOC in cluster A/B/C subtypes in GSE135820-HGSOC. A Consensus clustering matrix for k = 3. B Kaplan-Meier analysis of OS for patients with HGSOC in three clusters. C Differences in PD-1/PD-L1expression among three ICI clusters. D Unsupervised clustering of TIICs in GSE135820-HGSOC. Rows represent TIICs, and columns represent samples. E The fraction of TIICs in three ICI clusters. (Kruskal-Wallis test, *p < 0.05, **p < 0.01, ***p < 0.001, and ns p > 0.05). HGSOC, High-grade serous ovarian carcinoma; ICI, immune cell infiltration; OS, overall survival; TIICs, tumor-infiltrating immune cells; PD-1, programmed death-1; PD-L1, programmed death ligand 1

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BMC Genomics

ISSN: 1471-2164

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