Fig. 3
Clustering analysis of 22 3rd generation cephalosporin-resistant K. pneumoniae based on selected clinically relevant features (genes encoding antibiotic resistance, metal resistance, virulence, efflux systems, oxidative stress, quorum sensing and plasmid replicon types). A presence/absence table supported the Jaccard similarity index estimation and UPGMA clustering analysis. Colors in the table refer to the trait presence and different colors refer to different isolates MLST. Red, green, and blue symbols in the dendrogram refer to isolates obtained from patients, wastewater, and clinical settings, respectively. C-P – clinical isolate obtained from patients; C-E – isolate obtained from clinical environment; HE – hospital effluent; RWW – raw influent wastewater; sTWW – secondary treatment effluent wastewater; tTWW – tertiary treatment effluent wastewater