Skip to main content
Fig. 1 | BMC Genomics

Fig. 1

From: Cyclical regression covariates remove the major confounding effect of cyclical developmental gene expression with strain-specific drug response in the malaria parasite Plasmodium falciparum

Fig. 1

Errors caused by comparison of improperly aligned cyclical transcription data. A and B show two model features with identical expression patterns; C and D represent two model features with real differences in gene expression. A: When 0 hpi is correctly aligned for both, single observations (red bars) correctly detect no difference. B: When 0 hpi is improperly aligned, single observations (red bars) detect a difference between strains where none exists. C: Proper alignment of 0 hpi allows single observations (red bars) to detect the true difference. D: Improper alignment of 0 hpi obscures the true difference in single observations.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us