Fig. 4From: Cyclical regression covariates remove the major confounding effect of cyclical developmental gene expression with strain-specific drug response in the malaria parasite Plasmodium falciparumOverlap of genes considered significant before and after correction with GO Slim results. Comparison of the genes considered significantly correlated with patient clearance half-life in Groups A (A), B (B) and A+B (C) before (green) and after (purple) the application of cyclical regression covariate correction. D, E, and F show the comparison of up and downregulated GO Slim categories before and after the application of cyclical regression covariate correction for each group A, B, and A+B, respectively. Size of the point corresponds to the number of genes detected in the particular category and color corresponds to P-value.Back to article page