Table 2 The exploration of five class of active substances in W. pigra, H. medicinalis and H. robusta

Analgesic and anti-inflammatory effect

Antistasin

6

9

5

Hirustasin

0

18

7

Ghilanten

9

10

7

Extracellular matrix degradation

Hyaluronidase

1

4

5

Inhibition of platelet function

Saratin

1

4

1

Anticoagulant effect

hirudin

0

2

3

Factor Xa inhibitor

2

1

1

Therostasin

5

4

2

Destabilase I ^a

0

5

2

Antimicrobial effect

Destabilase I ^a

0

5

2

Total

24

57

33