Fig. 1

DNA insert size assessment of libraries prepared with enzymatic fragmentation and tagmentation. A Tapestation D1000 electorphoresis profiles for libraries prepared with 10 ng input DNA in four technical replicates each with Nextera DNA flex (Illumina), NEBNext Ultra II FS (NEB), Kapa Hyper Plus (Roche), SparQ DNA library (Quantabio) and Swift2S turbo flex (Swift) kits. DNA insert size of libraries was assessed from the sequencing reads of (B) libraries from 10 ng and (C) 100 ng DNA input after trimming of adapter sequences. The shaded regions are 95 % confidence intervals of the distributions sampled by the replicates (The band is hardly visible for Nextera, because the replicates are very similar)