Table 2 The top 10 outlier window positions from the body trait analysis based on corrected p-values that were within 25 kb of genes or regulatory regions up/downstream. The closest gene is listed for each window. Functions of each gene are abbreviated from RefSeq/Uniprot

ref0002232

15310000

1.71E-31

FLVCR2

This gene encodes a transmembrane protein that is a calcium transporter.

ref0000892

4172500

4.82E-29

SLC7A3

SLC7A3 appears to be involved in amino acid transmembrane transporter activity and basic amino acid transmembrane transporter.

ref0002547

2917000

2.98E-23

KRR1

KRR1 (KRR1 Small Subunit Processome Component Homolog) appears to be involved win cytosol and Gene Expression.

ref0000845

16369000

1.26E-20

CD163

Involved in the clearence and endocytocis of hemoglobin/heptaglobin complexes by macrophages. May protext tissues from free hemoglobin-mediated oxidative damage.

ref0000438

13320500

1.64E-20

KIF3C

Microtubule-based anterograde translocator for membranous organelles.

ref0002813

16028000

8.08E-20

DOCK1

This gene encodes a member of the dedicator of cytokinesis protein family.

ref0002788

19947500

2.45E-19

SYK

This gene encodes a member of the family of non-receptor type Tyr protein kinase that is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis.

ref0000529

431000

4.31E-19

TRDV1

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC).

ref0002645

24851500

8.41E-19

RNASEH1

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids

ref0002547

2916500

1.27E-18

KRR1

See above.