Fig. 7
The interaction network of genes and miRNAs of head development in bighead carp. a The interaction network for the top 20 key genes by Cytohubba. Different nodes meant different genes. The color depth of nodes was determined by the degree value. The higher the rank was, the darker the color was. b The miRNA-mRNA interaction network for key genes and miRNAs. Green rectangular boxes meant key genes. The lines between miRNA and mRNA meant the interactions between them. Gene abbreviations: Epidermal growth factor receptor (EGFR), Prothrombin (F2), Proteinase-activated receptor 1 (F2R), Fibronectin type III domain containing (FN1), Glucagon receptor (GCGR), Hepatocyte growth factor (HGF), Insulin-like growth factor I (IGF1), Integrin alpha-IIb (ITGA2B), Integrin beta-3 (ITGB3), Tyrosine-protein kinase JAK1 (JAK1), Vascular endothelial growth factor receptor 2 (KDR), Mast/stem cell growth factor receptor Kit (KIT), Platelet-derived growth factor receptor beta (PDGFRB), Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA), Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1), Signal transducer and activator of transcription 1-alpha/beta (STAT1), Signal transducer and activator of transcription 3 (STAT3), Thrombospondin-1 (THBS1), Vascular endothelial growth factor A (VEGFA), Von Willebrand factor (VWF)